Estrogen loss impairs NRF2-mediated antioxidant defenses, increasing susceptibility to infertility and cardiovascular disease in women. Sustained ROS-mediated oxidative stress and mitochondrial dysfunction in ovarian, vascular, and cardiac tissues underlie this mechanism.

Published 6 hours ago

Source: reddit.com

Estrogen loss impairs NRF2-mediated antioxidant defenses, increasing susceptibility to infertility and cardiovascular disease in women. Sustained ROS-mediated oxidative stress and mitochondrial dysfunction in ovarian, vascular, and cardiac tissues underlie this mechanism.

Estrogen loss impairs NRF2-mediated antioxidant defenses, increasing susceptibility to infertility and cardiovascular disease in women. Sustained ROS-mediated oxidative stress and mitochondrial dysfunction in ovarian, vascular, and cardiac tissues underlie this mechanism.

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